Your Wednesday Briefing – The New York Times

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Scientists at Imperial College London plan to deliberately infect volunteers with the coronavirus early next year, beginning the world’s first effort to study how vaccinated people respond to being intentionally exposed to the virus and opening up a new, uncertain path to identifying an effective vaccine.

The hotly contested strategy, known as a human challenge trial, could potentially shave crucial time in the race to winnow a number of vaccine candidates.

While the method has been used to test vaccines for typhoid, cholera and other diseases, Covid-19 has few widely used treatments and no known cure, putting the scientists in charge of Britain’s study in largely uncharted ethical territory.

Details: The scientists will first administer tiny doses of the virus to small groups of volunteers who have not been vaccinated, followed by tests in which volunteers are given a vaccine and then intentionally exposed to a carefully calibrated dose of the virus.

A battle over the lucrative lobster industry in Nova Scotia has turned violent. Commercial fishermen have burned down buildings and assaulted Indigenous fishermen, accusing them of threatening their livelihoods by trapping lobsters outside the regulated season. Above, a lobster pound that was burned to the ground over the weekend.

The members of the Sipekne’katik First Nation negotiated the right to hunt and fish in a centuries-old treaty, and a court has ruled in their favor. The fight over lobster is the latest flash point in a series of abuses of Indigenous people in Canada.

‘Golden passports’: Cyprus and Malta will face European Union penalties if they do not abandon lucrative programs that sell passports to foreigners. The two nations have a history of building opaque banking systems that have been used for illicit purposes, particularly by Russian and Asian billionaires.

Kim Wall’s killer: The Danish inventor convicted of killing the journalist aboard his homemade submarine in Copenhagen in 2017 briefly escaped from prison on Tuesday. He took a staff member hostage but was arrested a short time later.

Israel-U.A.E.: In the first official U.A.E. visit to Israel since the countries normalized relations, Emirati diplomats agreed to ease travel and upgrade West Bank checkpoints. Palestinians have called the alliance tacit assent to Israeli occupation.

U.S. election: President Trump and former Vice President Joe Biden will face off on Thursday for the last time before Nov. 3. This time, their microphones will be muted for parts of the debate to avoid interruptions like those by Mr. Trump that marred their first meeting. Mr. Biden leads Mr. Trump by nine percentage points, our poll found, and voters view him more favorably on almost every major issue.

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